Screen LibraryTrends in stem cell proliferation and cancer research /
The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiological processes that occur in normal stem cell biology. Some of the key oncogenic events in cancer and their signaling pathways that regulate cell divisi...
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| Corporate Authors: | |
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| Group Author: | ; |
| Published: |
Springer,
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| Publisher Address: | Dordrecht : |
| Publication Dates: | 2013. |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://dx.doi.org/10.1007/978-94-007-6211-4 |
| Summary: |
The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiological processes that occur in normal stem cell biology. Some of the key oncogenic events in cancer and their signaling pathways that regulate cell division cycle progression will be described considering prospects for using such knowledge in advanced cancer therapy. Each chapter shall provide an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance. |
| Item Description: | Includes index. |
| Carrier Form: | 1 online resource (xviii, 661 pages) : illustrations (some color) |
| ISBN: |
9789400762114 (electronic bk.) 9400762119 (electronic bk.) |
| Index Number: | RC268 |
| CLC: | R730.2 |
| Contents: |
Molecular Bases of Stem and Cancer Cell Proliferation. An Introduction to Proliferation and Migration of Stem and Cancer Cells / The Role of Cell Adhesion, Cell Junctions, and Extracellular Matrix in Development and Carcinogenesis / The Embryonic Rest Hypothesis of Cancer Development: 150 Years Later / Are Calcium Channels More Important Than Calcium Influx for Cell Proliferation? / Role of Calcium Signaling in Stem and Cancer Cell Proliferation / Formation and Function of Lipid Droplets in Inflammation and Cancer / The Role of Sphingolipids in Modulating Pluripotency of Stem Cells / Signaling Pathways Underlying Tumor Genesis, Proliferation and Cell Death. Signaling Pathways of Cbl-b and Its Role in Peripheral T Cell Tolerance / BH3-Only Proteins in Cancer and Apoptosis / Signaling Pathways of MTA Family Proteins as Regulators of Cancer Progression and Metastasis / Signalling Pathways of -Catenin/JNK in Carcinogenesis / The Regulation of the JNK Cascade and Programmed Cell Death by NF-KB: Mechanisms and Functions / Functions and Dysfunctions of Physiological Processes Involved in Tumor Genesis and Malignancy. Migration, Metastasis, and More: The Role of Chemokines in the Proliferation, Spreading, and Metastasis of Tumors / Autophagy, Cell Death, and Cancer / The Duality of Stem Cells: Double-Edged Sword in tumor Evolution and Treatment / Implications of Glioblastoma Stem Cells in Chemoresistance / The Tumor Microenvironment as a Transient Niche: A Modulator of Epigenetic States and Stem Cell Functions / Tumor-Associated Neutrophils / MicroRNA Control of Apoptotic Programs in Cancer / Strategies for Cancer Treatment. Markers of Cancer Stem Cells and Their Functions / Cancer Cell Dormancy: Potential Therapeutic Targets To Eradicate Cancer Cells Within the Niche / Modulating Apoptosis in Cancer Therapy with Ultrasound and High-Intensity Nanosecond Electric Pulses / Targeting the Cell Cycle for Cancer Treatment and Neuroprotection / |