Screen LibraryCarbohydrate recognition biological problems, methods, and applications /
"This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural...
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| Group Author: | ; |
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| Published: |
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| Literature type: | Electronic eBook |
| Language: | English |
| Series: |
Wiley series in drug discovery and development
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| Subjects: | |
| Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/9781118017586 |
| Summary: |
"This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition"--Provided by publisher. |
| Item Description: | Machine generated contents note: PREFACE. CONTRIBUTORS. 1 MAMMALIAN GLYCAN BIOSYNTHESIS : BUILDING A TEMPLATE FOR BIOLOGICAL RECOGNITION (M. Adam Meledeo, Venkata D.P. Paruchuri, Jian Du, Zhiyun Wang, and Kevin J. Yarema). 2 THE ROLES OF CARBOHYDRATE BINDING IN CELL ADHESION AND INFLAMMATION (Ken Kitajima and Chihiro Sato). 3 THE ROLE OF CARBOHYDRATES IN VIRAL INFECTIONS (Gillian M. Air). 4 THE ROLE OF CARBOHYDRATES IN BACTERIAL INFECTIONS (Roland J. Pieters). 5 THE ROLES OF CARBOHYDRATE BINDING IN FERTILIZATION (David J. Miller). 6 CARBOHYDRATE BIOMARKERS (Yunfeng Cheng, Nanting Ni, Hanjing Peng, Shan Jin, and Binghe Wang). 7 GALECTINS AND THEIR ROLE IN VARIOUS BIOLOGICAL PROCESSES (Sarika Saraswati, Ashley Stanley Block, and Alan B. Diekman). 8 GLYCOIMMUNOLOGY (Ani Grigorian and Barbara Newton). 9 TOOLS FOR GLYCOMICS: GLYCAN AND LECTIN MICROARRAYS (Jeff Gildersleeve). 10 COMBINATORIAL BIOSYNTHESIS OF COMPLEX CARBOHYDRATES (Hai Yu and Xi Chen). 11 MASS SPECTROMETRY IN CARBOHYDRATE SEQUENCING AND BINDING ANALYSIS (Gregory O. Staples and Joseph Zaia). 12 SYNTHETIC LECTIN MIMICS ARTIFICIAL CARBOHYDRATE RECEPTORS (Xiaochuan Yang, Yunfeng (Jerry) Cheng, and Binghe Wang). 13 LECTIN BINDING AND ITS STRUCTURAL BASIS (Annabelle Varrot, Bertrand Blanchard, and Anne Imberty). 14 MULTIVALENCY IN CARBOHYDRATE BINDING (Mark L. Wolfenden and Mary J. Cloninger). 15 CARBOHYDRATE BINDING AGENTS : POTENTIAL THERAPEUTICS WITH MULTIPLE INHIBITORY ACTIONS AGAINST ENVELOPED VIRUSES (K.O. Francois and J. Balzarini). 16 INFORMATICS FOR GLYCOBIOLOGY AND GLYCOMICS (Kiyoko F. Aoki-Kinoshita). INDEX. |
| Carrier Form: | 1 online resource. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9781118017586 (electronic bk.) 1118017587 (electronic bk.) 9781118017562 (electronic bk.) 1118017560 (electronic bk.) 1283227886 9781283227889 |
| Index Number: | QP701 |
| CLC: | Q53 |
| Contents: | Frontmatter -- Color Plates -- Mammalian Glycan Biosynthesis: Building a Template for Biological Recognition / M Adam Meledeo, Venkata D P Paruchuri, Jian Du, Zhiyun Wang, Kevin J Yarema -- The Roles of Carbohydrate Binding in Cell Adhesion and Inflammation / Ken Kitajima, Chihiro Sato -- The Role of Carbohydrates in Viral Infections / Gillian M Air -- The Role of Carbohydrates in Bacterial Infections / Roland J Pieters -- The Roles of Carbohydrate Binding in Fertilization / David J Miller -- Carbohydrate Biomarkers / Yunfeng Cheng, Nanting Ni, Hanjing Peng, Shan Jin, Binghe Wang -- Galectins and their Role in Various Biological Processes / Sarika Saraswati, Ashley Stanley Block, Alan B Diekman -- Glycoimmunology / Ani Grigorian, Barbara Newton, Michael Demetriou -- Tools for Glycomics: Glycan and Lectin Microarrays / Christopher Campbell, Jeff Gildersleeve -- Combinatorial Biosynthesis of Complex Carbohydrates / Hai Yu, Xi Chen -- Mass Spectrometry in Carbohydrate Sequencing and Binding Analysis / Gregory O Staples, Joseph Zaia -- Synthetic Lectin Mimics Artificial Carbohydrate Receptors / Xiaochuan Yang, Yunfeng Cheng, Binghe Wang -- Lectin Binding and its Structural Basis / Annabelle Varrot, Bertrand Blanchard, Anne Imberty -- Multivalency in Carbohydrate Binding / Mark L Wolfenden, Mary J Cloninger -- Carbohydrate Binding Agents: Potential Therapeutics with Multiple Inhibitory Actions against Enveloped Viruses / K O Fraṅois, J Balzarini -- Informatics for Glycobiology and Glycomics / Kiyoko F Aoki-Kinoshita -- Index. |