Screen LibraryAminoglycoside antibiotics from chemical biology to drug discovery /
Advances that open new avenues in developing aminoglycoside antibiotics. During the last twenty years, there have been numerous advances in the understanding of the chemistry, biochemistry, and recognition of aminoglycosides. This has led to the development of novel antibiotics and opened up new the...
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| Literature type: | Electronic eBook |
| Language: | English |
| Series: |
Wiley series in drug discovery and development
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| Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/9780470149676 |
| Summary: |
Advances that open new avenues in developing aminoglycoside antibiotics. During the last twenty years, there have been numerous advances in the understanding of the chemistry, biochemistry, and recognition of aminoglycosides. This has led to the development of novel antibiotics and opened up new therapeutic targets for intervention. |
| Carrier Form: | 1 online resource (x, 319 pages, [8] pages of plates) : illustrations (some color) |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9780470149676 0470149671 9780470149669 0470149663 1280900393 9781280900396 |
| Index Number: | RM666 |
| CLC: | R282.71 |
| Contents: | AMINOGLYCOSIDE ANTIBIOTICS; CONTENTS; Preface; Contributors; 1. In the Beginning There Was Streptomycin; 2. The Biochemistry and Genetics of Aminoglycoside Producers; 3. Mechanisms of Aminoglycoside Antibiotic Resistance; 4. Design, Chemical Synthesis, and Antibacterial Activity of Kanamycin and Neomycin Class Aminoglycoside Antibiotics; 5. NMR Structural Studies of Aminoglycoside: RNA Interaction; 6. Structural Comparisons Between Prokaryotic and Eukaryotic Ribosomal Decoding A Sites Free and Complexed with Aminoglycosides. |