Screen LibraryMammalian cell biotechnology in protein production /
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| Corporate Authors: | |
|---|---|
| Group Author: | ; |
| Published: |
De Gruyter,
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| Publisher Address: | Berlin ;Boston : |
| Publication Dates: |
[2011] ©1997 |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://dx.doi.org/10.1515/9783110809282 http://www.degruyter.com/doc/cover/9783110809282.jpg |
| Carrier Form: | 1 online resource (491pages) |
| ISBN: | 9783110809282 |
| Index Number: | TP248 |
| CLC: | TQ93 |
| Contents: |
Frontmatter -- Preface -- Contents -- Contributors List -- 1. Genetic Manipulation of Mammalian Cells -- 1.1 Heterologous Expression of Genes in Mammalian Cells -- 1.2 Permanent Gene Expression in Mammalian Cells: Gene Transfer And Selection -- 1.3 Vectors for Gene Transfer and Expression in Animal Cells -- 1.4 Aspects of Gene Transfer and Gene Amplification in Recombinant Mammalian Cells -- 1.5 Isolation of Recombinant Cell Clones Exhibiting High-Level Expression of the Introduced Gene -- 1.6 Genetic Engineering of Antibodies and Derivatives from Mammalian Cells -- 1.7 Safety Evaluation of Products Derived From Mammalian Cell Lines -- 2. Biological Aspects of Animal Cells -- 2.1 Metabolic Control of Animal Cell Culture Processes -- 2.2 Glycosylation: A Post-Translational Modification -- 3. Cell Cultivation Technology -- 3.1 Bioreactors Designed for Animal Cells -- 3.2 Hydrodynamic Properties in Bioreactors -- 3.3 Kinetics and Simulation of Animal Cell Processes -- 3.4 On-line and Off-line Process Analysis -- 4. Down-Stream Processing -- 4.1 Principles of Product Extraction from Cell Culture and Purification for Pharmaceutical Proteins -- 4.2 Validation of Downstream Processes -- Index -- Backmatter |