Clinical pharmacokinetics and pharmacodynamics:concepts and applications
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Main Authors: | |
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Group Author: | |
Published: |
Wolters Kluwer Health/Lippincott William & Wilkins,
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Publisher Address: | Philadelphia |
Publication Dates: | c2011. |
Literature type: | Book |
Language: | English |
Edition: | 4th ed. |
Subjects: | |
Item Description: | Clinical pharmacokinetics. |
Carrier Form: | xxii, 839 p.: ill. ; 26 cm. |
ISBN: |
9780781750097 0781750091 |
Index Number: | R969 |
CLC: | R969.1 |
Call Number: | R969.1/R883/4th.ed. |
Contents: |
Rev. ed. of: Clinical pharmacokinetics. 1995. Includes index. Therapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple-dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data. |