Screen LibraryProtein secretion in bacteria /
"Protein transport into and across membranes is a fundamental process in bacteria that touches upon and unites many areas of microbiology, including bacterial cell physiology, adhesion and motility, nutrient scavenging, intrabacterial signaling and social behavior, toxin deployment, interbacter...
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| Group Author: | ; ; |
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| Published: |
ASM Press,
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| Publisher Address: | Washington, DC : |
| Publication Dates: | [2019] |
| Literature type: | Book |
| Language: | English |
| Subjects: | |
| Summary: |
"Protein transport into and across membranes is a fundamental process in bacteria that touches upon and unites many areas of microbiology, including bacterial cell physiology, adhesion and motility, nutrient scavenging, intrabacterial signaling and social behavior, toxin deployment, interbacterial antagonism and collaboration, host invasion and disruption, and immune evasion. A broad repertoire of mechanisms and macromolecular machines are required to deliver protein substrates across bacterial cell membranes for intended effects. Some machines are common to most, if not all bacteria, whereas others are specific to Gram-negative or Gram-positive species or species with unique cell envelope properties such as members of Actinobacteria and Spirochetes. Protein Secretion in Bacteria, authored and edited by an international team of experts, draws together the many distinct functions and mechanisms involved in protein translocation in one concise tome. This comprehensive book presents updated information on all aspects of bacterial protein secretion encompassing: Individual secretory systems-Sec, Tat, and T1SS through the newly discovered T9SS Mechanisms, structures, and functions of bacterial secretion systems Lipoprotein sorting pathways, outer membrane vesicles, and the sortase system Structures and roles of surface organelles, including flagella, pili, and curli Emerging technologies and translational implications Protein Secretion in Bacteria serves as both an introductory guide for students and postdocs, and a ready reference for seasoned researchers whose work touches on protein export and secretion. This volume synthesizes the diversity of mechanisms of bacterial secretion across the microbial world into a digestible resource to stimulate new research, inspire continued identification and characterization of novel systems, and bring about new ways to manipulate these systems for biotechnological, preventative, and therapeutic applications"-- |
| Carrier Form: | xxii, 410 pages : illustrations (chiefly color), forms ; 26 cm |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9781683670278 (hardcover) : 1683670272 (hardcover) 9781683670285 (electronic book) 1683670280 (electronic book) |
| Index Number: | QR92 |
| CLC: | Q936 |
| Call Number: | Q936/P967 |
| Contents: |
Electron cryotomography of bacterial secretions systems / SecA-Mediated protein translocation through the SecYEG Channel / The two distinct types of SecA2-dependent export systems / The conserved role of YidC in membrane protein biogenesis / The twin-arginine pathway for protein secretion / Lipoproteins and their trafficking to the outer membrane / Protein secretion in spirochetes / Outer membrane protein insertions by the [beta]-barrel assembly machine / The TAM: a translocation and assembly module of the [beta]-barrel assembly machinery in bacterial outer membranes / The dynamic structures of the Type IV Pilus / Gram-postive Type IV Pili and competence / The remarkable biomechanical properties of the Type 1 Chaperone-Usher Pilus: a structural and molecular perspective / Therapeutic approaches targeting the assembly and function of Chaperone-Usher Pili / Curli biogenesis: bacterial amyloid assembly by the Type VIII secretion pathway / Sortases, surface proteins, and their roles in Staphylococcus aureus disease and vaccine development / Architecture and assembly of periplasmic flagellum / Outer membrane vesicle-host cell interactions / Type I secretion systems--One mechanism for all? / Architecture, function, and substrates of the Type II secretion system / The injectisome, a complex nanomachine for protein injection into mammalian cells / Promises and challenges of the type three secretion system injectisome as an antivirulence target / Biological and structual diversity of Type IV secretions systems / Hostile takeover: hijacking of endoplasmic reticulum function by T4SS ant T3SS effectors creates a niche for intracellular pathogens / Type V secretion in gram-negative bacteria / Brodetella Filamentous Hemagglutinin, a model for the two-partner secretion pathway / Structure and activity of the Type VI secretion system / Type VI secretion systems and the gut microbiota / ESX/Type VII secretion systems--An important way out for mycobacterial proteins / Bacteroidetes gliding motility and the Type IX secretions system / Similarities and differences between colicin and filamentous phage uptake by bacterial cells / A hybrid secretion system facilitates bacterial sporulation: a structural perspective / |