Screen LibraryThe base excision repair pathway : molecular mechanisms and role in disease development and therapeutic design /
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| Group Author: | |
|---|---|
| Published: |
World Scientific,
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| Publisher Address: | Singapore : |
| Publication Dates: | [2017] |
| Literature type: | Book |
| Language: | English |
| Subjects: | |
| Carrier Form: | xiv, 808 pages : illustrations (some color), forms ; 24 cm |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9789814719728 (hardback) : 9814719722 (hardback) |
| Index Number: | QH467 |
| CLC: | Q523 |
| Call Number: | Q523/B299 |
| Contents: | Genomic uracil : dangers and benefits in processing / Hans Krokan -- The GO repair pathway : OGG1 and MUTYH / Sheila David -- The DNA glycosylases that recognize and remove free radical-damaged pyrimidines / Susan Wallace -- Alkyladenine DNA glycosylase / Leona Samson -- The abasic endonuclease APE1 : much more than a DNA repair enzyme / Gianluca Tell -- Central steps in mammalian BER and regulation by PARP1 / Samuel Wilson -- Processing strand break termini in the DNA single strand break repair pathway / Michael Weinfeld -- The PARP-XRCC1 axis in base excision repair / Janet Hall -- DNA ligases in base excision repair / Alan Tomkinson -- Base excision repair and epigenetic regulation / Primo Schär -- Base excision repair in the immune system / Carol Schrader -- Base excision repair in the etiology of lupus and cancer / Joann Sweasy -- Base excision repair in trinucleotide repeat expansion disorders / Margherita Bignami -- Neurodegeneration caused by accumulation of an oxidized base lesion, 8-oxoguanine, in nuclear and mitochondrial DNA: from animal models to human diseases / Yusaku Nakabeppu -- Assessing BER capacity in the human population / Zachary Nagel -- Prognostic and predictive significance of base excision repair in human cancers / Srinivasan Madhusudan -- Enzymes in the base excision repair pathway as targets for small molecule mediated therapeutics / R. Stephen Lloyd -- Mitochondrial base excision repair / Nadja de Souza Pinto -- Base excision repair in aging / Tinna Stevnsner. |