Screen LibraryBasic pharmacology /
Basic Pharmacology, Third Edition aims to present accounts of drug actions and their mechanisms in a compact, inexpensive, and updated form, and explain the basis of the therapeutic exploitation of drugs. This book is divided into sections that follow a particular theme and is introduced by the rele...
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| Corporate Authors: | |
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| Group Author: | ; |
| Published: |
Butterworth-Heinemann,
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| Publisher Address: | Oxford ; Boston : |
| Publication Dates: | 1991. |
| Literature type: | eBook |
| Language: | English |
| Edition: | Third edition. |
| Subjects: | |
| Online Access: |
http://www.sciencedirect.com/science/book/9780750614146 |
| Summary: |
Basic Pharmacology, Third Edition aims to present accounts of drug actions and their mechanisms in a compact, inexpensive, and updated form, and explain the basis of the therapeutic exploitation of drugs. This book is divided into sections that follow a particular theme and is introduced by the relevant pharmacological general principles. In each section, the major groups of drugs related to the theme are discussed with detailed expositions of the important "type” substances. Drugs of lesser importance are placed in proper context. A list of abbreviations that are referenced throughout |
| Carrier Form: | 1 online resource (xvii, 461 pages) : illustrations |
| Bibliography: | Includes bibliographical references (pages 441-442) and index. |
| ISBN: |
9781483142029 1483142027 |
| Index Number: | RM300 |
| CLC: | R96 |
| Contents: |
Front Cover; Basic Pharmacology; Copyright Page; Table of Contents; Preface; Introduction; List of abbreviations; Chapter 1. General pharmacology; Mechanisms of drug action; Receptor mediation of drug effects; Adverse effects of drugs; Allergically determined hypersensitivity to drugs; Genetically determined idiosyncracy to drugs (pharmacogenetics); Developmental toxicity; Adverse drug interactions; Abuse of drugs; Drug design, development and testing. Chapter 2. Drug action on peripheral excitable tissues -- drugs acting on signalling and transduction mechanisms directly related to receptors for the neurotransmitters acetylcholine and noradrenalineAnatomy and physiology of the (efferent) peripheral nervous system and its effectors; The effector cells innervated by postganglionic autonomic neurones: important effects caused by nervous activity; The pharmacology of cholinergic axons and their terminals; The pharmacology of the cholinoceptors of skeletal muscle; The pharmacology of the cholinoceptors of ganglia. The pharmacology of the cholinoceptors of smooth muscle, cardiac muscle and exocrine glandsCholinesterases and their inhibitors; Noradrenergic neuroeffector transmission as a target of drug action; Drugs with noradrenergic prejunctional sites of action; Drugs that modify the release of noradrenaline; Drugs that modify the inactivation of noradrenaline; Agonists at adrenoceptors; Antagonists at adrenoceptors; The adrenal medulla. Chapter 3. Drug action on peripheral tissues -- drugs acting on signalling and transduction mechanisms other than those directly related to receptors for neurotransmitters and hormoneshormones; Local anaesthesia; Cardiac antidysrhythmic drugs; Cardiac glycosides; Calcium channel blockers; Methylxanthines; Nitrates; Diuretics; Anticoagulant, antithrombotic and fibrinolytic compounds; Lipid-lowering drugs; Chapter 4. Endocrine pharmacology; Hypothalamo-pituitary axis; Gonadotrophins; Oestrogens, progestogens and androgens; The thyroid gland and drugs used in thyroid abnormalities. The adrenal cortex and the corticosteroidsDrugs in diabetes mellitus; Posterior pituitary hormones; Angiotensin; Local hormones; Inflammation; Chapter 5. Drug action on the central nervous system; Chemical transmission in the CNS; Extrapyramidal disorders of movement; Antidepressive drugs; Antipsychotic drugs; Vomiting, emetics and antiemetics; Opioid analgesics and their antagonists; Stimulants and hallucinogens; Antipyretic analgesics; The state of consciousness and the general anaesthetic agents; Chapter 6. Antiparasitic chemotherapy; Biochemical selectivity; Distributional selectivity. |