Intrinsically disordered proteins : dynamics, binding, and function /

Intrinsically Disordered Proteins: Dynamics, Binding, and Function thoroughly examines and ties together the fundamental biochemical functions of intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs), including signaling, binding, and regulation, with the methodology f...

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Bibliographic Details
Corporate Authors: Elsevier Science & Technology.
Group Author: Salvi, Nicola
Published: Academic Press,
Publisher Address: London :
Publication Dates: [2019]
©2019
Literature type: eBook
Language: English
Edition: First edition.
Subjects:
Online Access: https://www.sciencedirect.com/science/book/9780128163481
Summary: Intrinsically Disordered Proteins: Dynamics, Binding, and Function thoroughly examines and ties together the fundamental biochemical functions of intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs), including signaling, binding, and regulation, with the methodology for study and the associated pathways for drug design and therapeutic intervention. The role of new mechanistic, computational, and experimental approaches in IDP study are explored in depth, with methods for the characterization of IDP dynamics; models, simulations, and mechanisms of IDP and IDR binding; and biological and medical implications of IDP dynamics prominently featured. Written and edited by leading scientists in the field, this book explores groundbreaking areas such as ensemble descriptions of IDPs and IDRs, single-molecule studies of IDPs and IDRs, IDPs and IDRs in membraneless organelles, and molecular mechanisms of fibrillation of IDPs. Intrinsically Disordered Proteins provides students and researchers in biochemistry, molecular biology, and applied microbiology with a comprehensive and updated discussion of the complex dynamics of IDPs and IDRs.
Carrier Form: 1 online resource : color illustrations
Bibliography: Includes bibliographical references and index.
ISBN: 9780128167328
0128167327
9780128163481
0128163488
Index Number: QP551
CLC: Q51