Antibiotics:actions, origins, resistance
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Main Authors: | |
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Published: |
ASM Press,
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Publisher Address: | Washington, D.C. |
Publication Dates: | c2003. |
Literature type: | Book |
Language: | English |
Subjects: | |
Carrier Form: | x, 335 p.: ill. (some col.) ; 26 cm. |
ISBN: | 1555812546 |
Index Number: | R978 |
CLC: | R978.1 |
Call Number: | R978.1/W223 |
Contents: |
Includes bibliographical references (p. 297-328) and index. Antibiotics : initial concepts -- Introduction to major antibiotic classes and modes of action -- Antibiotics that act on cell wall biosynthesis -- Antibiotics that block bacterial protein biosynthesis -- Antibiotics that block DNA replication and repair : the Quinolones -- Other targets of antibacterial drugs -- Natural and producer immunity versus acquired resistance -- Enzymatic destruction or modification of the antibiotic by resistant bacteria -- Antibiotic resistance by efflux pumps -- Antibiotic resistance by replacement or modification of the antibiotic target -- Regulation of antibiotic biosynthesis in producer organisms -- Polyketide antibiotic biosynthesis : assembly line enzymology -- Enzymatic assembly lines for nonribosomal peptide antibiotics -- Biosynthesis of other classes of antibiotics -- New looks at targets -- New molecules -- Contexts and challenges for the use of new antibiotics. |