Contemporary drug synthesis
An integrated and insightful look at successful drug synthesis in today's drug discovery market The pharmaceutical industry is unquestionably vibrant today, with drug synthesis making a vital contribution. Whether in the early developmental stages of identifying and optimizing a lead, or the la...
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Published: |
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Literature type: | eBook |
Language: | English |
Subjects: | |
Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/0471686743 |
Summary: |
An integrated and insightful look at successful drug synthesis in today's drug discovery market The pharmaceutical industry is unquestionably vibrant today, with drug synthesis making a vital contribution. Whether in the early developmental stages of identifying and optimizing a lead, or the latter stages of process development and cost-effective scale-up, the ability to design elegant and economical synthetic routes is often a major factor in the eventual viability and commercial success of a drug. |
Carrier Form: | 1 online resource (xv, 221 pages) : illustrations |
Bibliography: | Includes bibliographical references and index. |
ISBN: |
0471686735 9780471686736 9780471686743 0471686743 |
Index Number: | RS403 |
CLC: | R914 |
Contents: | Antithrombotics : Ticlopidine (Ticlid) and Clopidogrel (Plavix) -- Anti-inflammatory cyclooxygenase-2 selective inhibitors : Celecoxib (Celebrex) and Rofecoxib (Vioxx) -- H+/K+ -ATPase inhibitors : Esomeprazole (Nexium) -- Protein-tyrosine kinase inhibitors : Imatnib (Gleevec) and Gefitinib (Iressa) -- Non-sedating antihistamines -- Cosmeceuticals : Istretinoin (Accutane), Tazarotene (Tazorac), Minoxidil (Rogaine), and Finasteride (Propecia) -- Antibacterials : Ciprofloxacin (Cipro) and Linezolid (Zyvox) -- Atypical antipsychotics -- Atovastatin calcium (Lipitor) -- Antidepressants -- Anti-obesity : Orlistat (Xenical) -- Triptans for migrane -- PDE 5 inhibitors for erectile dysfunction : Sildenafil (Viagra), Vardenafil (Levitra), and Tadalafil (Cialis) -- Antiasthmatics. |