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Contemporary drug synthesis

An integrated and insightful look at successful drug synthesis in today's drug discovery market The pharmaceutical industry is unquestionably vibrant today, with drug synthesis making a vital contribution. Whether in the early developmental stages of identifying and optimizing a lead, or the la...

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Bibliographic Details
Group Author: Li, Jie Jack.
Published:
Literature type: eBook
Language: English
Subjects:
Pharmaceutical chemistry.
Drug Design.
Chemistry, Pharmaceutical > methods.
Chimie pharmaceutique.
MEDICAL > Pharmacology.
Synthetic drugs.
Drug development.
Organic Chemistry.
FACsci
ER > Internet > Book > Full text
Electronic books.
Online Access: http://onlinelibrary.wiley.com/book/10.1002/0471686743
Summary: An integrated and insightful look at successful drug synthesis in today's drug discovery market The pharmaceutical industry is unquestionably vibrant today, with drug synthesis making a vital contribution. Whether in the early developmental stages of identifying and optimizing a lead, or the latter stages of process development and cost-effective scale-up, the ability to design elegant and economical synthetic routes is often a major factor in the eventual viability and commercial success of a drug.
Carrier Form: 1 online resource (xv, 221 pages) : illustrations
Bibliography: Includes bibliographical references and index.
ISBN: 0471686735
9780471686736
9780471686743
0471686743
Index Number: RS403
CLC: R914
Contents: Antithrombotics : Ticlopidine (Ticlid) and Clopidogrel (Plavix) -- Anti-inflammatory cyclooxygenase-2 selective inhibitors : Celecoxib (Celebrex) and Rofecoxib (Vioxx) -- H+/K+ -ATPase inhibitors : Esomeprazole (Nexium) -- Protein-tyrosine kinase inhibitors : Imatnib (Gleevec) and Gefitinib (Iressa) -- Non-sedating antihistamines -- Cosmeceuticals : Istretinoin (Accutane), Tazarotene (Tazorac), Minoxidil (Rogaine), and Finasteride (Propecia) -- Antibacterials : Ciprofloxacin (Cipro) and Linezolid (Zyvox) -- Atypical antipsychotics -- Atovastatin calcium (Lipitor) -- Antidepressants -- Anti-obesity : Orlistat (Xenical) -- Triptans for migrane -- PDE 5 inhibitors for erectile dysfunction : Sildenafil (Viagra), Vardenafil (Levitra), and Tadalafil (Cialis) -- Antiasthmatics.

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