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Transporters as drug carriers structure, function, substrates /

This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mamma...

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Bibliographic Details
Corporate Authors: Wiley InterScience (Online service)
Group Author: Ecker, Gerhard.; Chiba, Peter.
Published:
Literature type: eBook
Language: English
Series: Methods and principles in medicinal chemistry ; v. 44.
Subjects:
Drug carriers (Pharmacy)
Drugs > Physiological transport.
Drug Resistance.
MEDICAL > Drug Guides.
MEDICAL > Pharmacology.
MEDICAL > Pharmacy.
MEDICAL > Pharmacology. > Pharmacology.
Drug Carriers.
Biological Transport > drug effects.
Biological Transport > physiology.
Electronic books.
Online Access: http://onlinelibrary.wiley.com/book/10.1002/9783527627424
Summary: This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with special attention given to transport across those physiological barriers relevant for drug uptake, distribution and excretion. As a result, this key resource lays the foundations for understanding and investigat.
Carrier Form: 1 online resource (xx, 429 pages) : illustrations (some color).
Bibliography: Includes bibliographical references and index.
ISBN: 9783527627424
3527627421
9783527627431 (electronic bk.)
352762743X (electronic bk.)
Index Number: QP552
CLC: R969.1
Contents: Transporters as Drug Carriers: Structure, Function, Substrates; Contents; List of Contributors; Preface; A Personal Foreword; Part One: Human Transporter Families -- Structure, Function, Physiology; 1 The ABC Transporters: Structural Insights into Drug Transport; 2 Biochemistry, Physiology, and Pharmacology of Nucleoside and Nucleobase Transporters; 3 Organic Anion Transporting Polypeptides (Oatps/OATPs); 4 CNS -- Transporters as Drug Targets; Part Two: Drug Transport in Microorganisms and Fungi; 5 Bacterial Multidrug Transporters: Molecular and Clinical Aspects.

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