Transporters as drug carriers structure, function, substrates /
This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mamma...
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Corporate Authors: | |
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Group Author: | ; |
Published: |
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Literature type: | eBook |
Language: | English |
Series: |
Methods and principles in medicinal chemistry ; v. 44. |
Subjects: | |
Online Access: |
http://onlinelibrary.wiley.com/book/10.1002/9783527627424 |
Summary: |
This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with special attention given to transport across those physiological barriers relevant for drug uptake, distribution and excretion. As a result, this key resource lays the foundations for understanding and investigat. |
Carrier Form: | 1 online resource (xx, 429 pages) : illustrations (some color). |
Bibliography: | Includes bibliographical references and index. |
ISBN: |
9783527627424 3527627421 9783527627431 (electronic bk.) 352762743X (electronic bk.) |
Index Number: | QP552 |
CLC: | R969.1 |
Contents: | Transporters as Drug Carriers: Structure, Function, Substrates; Contents; List of Contributors; Preface; A Personal Foreword; Part One: Human Transporter Families -- Structure, Function, Physiology; 1 The ABC Transporters: Structural Insights into Drug Transport; 2 Biochemistry, Physiology, and Pharmacology of Nucleoside and Nucleobase Transporters; 3 Organic Anion Transporting Polypeptides (Oatps/OATPs); 4 CNS -- Transporters as Drug Targets; Part Two: Drug Transport in Microorganisms and Fungi; 5 Bacterial Multidrug Transporters: Molecular and Clinical Aspects. |