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CLC: N - 自然科学总论

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Orphan G protein-coupled receptors and novel neuropeptides

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Bibliographic Details
Corporate Authors: SpringerLink (Online service)
Group Author: Zhou Qun-Yong.; Civelli Olivier.
Published: Springer,
Publisher Address: Berlin
Publication Dates: c2008.
Literature type: Book
Language: English
Series: Results and problems in cell differentiation ; 46
Subjects:
Receptors, G-Protein-Coupled.
Neuropeptides.
Receptors, Neuropeptide.
Electronic books.
G proteins.
Methodology
Receptors
Research
Science.
Physiology.
Natural history
MEDICAL > Neuroscience.
PSYCHOLOGY > Neuropsychology.
ECHO-Viren.
G-Proteine.
Rezeptor.
Neuropeptide.
G proteins > Receptors > Research > Methodology.
Online Access: http://dx.doi.org/10.1007/978-3-540-78351-0
Carrier Form: 1 online resource (xv, 259 p.): ill. (some col.)
ISBN: 9783540783510 (electronic bk.)
3540783512 (electronic bk.)
Index Number: Q51
CLC: Q51
Contents: Includes bibliographical references and index.
The orphanin FQ/Nociceptin (OFQ/N) system / Olivier Civelli -- Orexins and orexin receptors: from molecules to integrative physiology / Taizo Matsuki, Takeshi Sakurai -- Prolactin-releasing peptide / Steven H. Lin -- Structure and function of ghrelin / Masayasu Kojima, Kenji Kangawa -- GPR54 and kisspeptins / W.H. Colledge -- Neuropeptide S: anatomy, pharmacology, genetics and physiological functions / Rainer K. Reinscheid -- The melanin-concentrating hormone system and its physiological functions / Yumiko Saito, Hiroshi Nagasaki -- Biological function of prokineticins / Q.-Y. Zhou, R. Meidan -- Neuromedin S.: discovery and functions / Kenji Mori, Mikiya Miyazato, Kenji Kangawa -- Relaxin-3, INSL5, and their receptors / Changlu Liu, Timothy W. Lovenberg -- The NPB/NPW neuropeptide system and its role in regulating energy homeostasis, pain, and emotion / Mari Hondo, Makoto Ishii, Takeshi Sakurai.
Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physiological or behavioral responses. For example the orexins, MCH and ghrelin carry fundamental roles in regulating food intake while neuropeptide S, neuromedin S, the prokineticins and the orexins are major players in modulating sleep and circadian rhythms. The chapters of this book review the latest

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