Bayesian adaptive methods for clinical trials
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Group Author: | |
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Published: |
CRC Press,
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Publisher Address: | Boca Raton |
Publication Dates: | c2011. |
Literature type: | Book |
Language: | English |
Series: |
Chapman & Hall/CRC biostatistics series ; 38 |
Subjects: | |
Carrier Form: | xvii, 305 p.: ill. ; 25 cm. |
ISBN: |
9781439825488 (hbk.) 1439825483 (hardcover : alk. paper) |
Index Number: | O212 |
CLC: |
O212.5 R446.1 |
Call Number: | R446.1/B357 |
Contents: |
Includes bibliographical references and indexes. Statistical approaches for clinical trials -- Basics of Bayesian inference -- Phase I studies -- Phase II studies -- Phase III studies -- Special topics. "As has been well-discussed, the explosion of interest in Bayesian methods over the last 10 to 20 years has been the result of the convergence of modern computing power and ełcient Markov chain Monte Carlo (MCMC) algo- rithms for sampling from and summarizing posterior distributions. Prac- titioners trained in traditional, frequentist statistical methods appear to have been drawn to Bayesian approaches for three reasons. |