Screen LibraryHalogenated biphenyls, terphenyls, naphthalenes, dibenzodioxins, and related products /
The chemical industry is increasingly faced with problems arizing from chemicals produced during the manufacture of halogenated biphenyls or phenols. Knowledge of these chemicals and their destructive properties is sporadic, and the acute toxicity of this group varies widely. This informative revise...
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| Corporate Authors: | |
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| Group Author: | ; |
| Published: |
Elsevier ; Sole distributors for the USA and Canada, Elsevier Science Pub. Co.,
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| Publisher Address: | Amsterdam : New York, NY, USA : |
| Publication Dates: | 1989. |
| Literature type: | eBook |
| Language: | English |
| Edition: | 2nd edition. |
| Series: |
Topics in environmental health ;
volume 4 |
| Subjects: | |
| Online Access: |
http://www.sciencedirect.com/science/book/9780444810298 |
| Summary: |
The chemical industry is increasingly faced with problems arizing from chemicals produced during the manufacture of halogenated biphenyls or phenols. Knowledge of these chemicals and their destructive properties is sporadic, and the acute toxicity of this group varies widely. This informative revised edition presents the chemistry, environmental pollution problems, animal toxicology and information about structure-activity relationships. A brief overview is given of worker exposure and occupational illness. The book is divided into three parts: chemistry and environmental contamination; experimental toxicology; and human exposure and effects. Because of the great deal of interest in these compounds much new research work has been conducted since the first edition of this book was published. This revised edition has retained the effectiveness and clarity of the first edition, while being supplemented with new information, condensed old information, and examples of recent incidents. |
| Carrier Form: | 1 online resource (xv, 518 pages) : illustrations. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9780444598929 0444598928 |
| Index Number: | RA1242 |
| CLC: | R996 |
| Contents: |
Front Cover; Halogenated Biphenyls, Terphenyls, Naphthalenes, Dibenzodioxins and Related Products; Copyright Page; Preface; Abbreviations; Table of contents; Part I: Chemistry, usage and environmental contamination; Chapter 1. Production, properties and usage of polychlorinated biphenyls; 1.1. Production; 1.2. Properties; 1.3. Applications and consumption; References; Appendix I; Chapter 2. Chemical properties, analytical methods and environmental levels of PCBs, PCTs, PCNs and PBBs; 2.1. Introduction; 2.2. Polychlorinated biphenyls; 2.3. Polychlorinated terphenyls (PCTs). 2.4. Polychlorinated naphthalenes (PCNs)2.5. Polybrominated biphenyls (PBBs); References; Chapter 3. Chemical and physical properties, analytical methods, sources and environmental levels of halogenated dibenzodioxins and dibenzofurans; 3.1. Chemical and physical properties; 3.2. Analytical methods; 3.3. Sources of human exposure and environmental contamination; 3.4. Environmental levels; References; Chapter 4. Effects on fish and wildlife populations; 4.1. Introduction; 4.2. Case histories; 4.3. Discussion; Acknowledgements; References. PART II: Toxicokinetics, in vitro tests, and animal toxicityChapter 5. Polyhalogenated aromatics: uptake, disposition and metabolism; 5.1. Introduction; 5.2. Absorption; 5.3. Disposition; 5.4. Fetal accumulation of halogenated aromatics; 5.5. Metabolism; Acknowledgements; References; Chapter 6. Acute and chronic toxicity and carcinogenesis in animals; 6.1. Introduction; 6.2. Toxicity; 6.3. Carcinogenesis; References; Chapter 7. Reproductive and developmental toxicity in animals; 7.1. Introduction; 7.2. Reproduction; 7.3. Developmental toxicity. 7.4. Structure-activity and species considerationsReferences; Chapter 8. Genetic toxicity; 8.1. Introduction; 8.2. Polychlorinated biphenyls; 8.3. Polybrominated biphenyls; 8.4. Polychlorinated dibenzodioxins; 8.5. Polychlorinated naphthalenes; 8.6. Polychlorinated dibenzofurans; 8.7. Summary; Acknowledgement; References; Chapter 9. Mechanism of action and structure-activity relationships for the chlorinated dibenzo-p-dioxins and related compounds; 9.1. Introduction; 9.2. Evidence for a receptor; 9.3. Toxic effects of TCDD; 9.4. Biochemical effects of 2,3,7,8-TCDD and related compounds. 9.5. Structure-activity relationships9.6. Summary; Acknowledgements; References; Chapter 10. Immune alterations; 10.1. Introduction; 10.2. The immune system; 10.3. Polychlorinated biphenyls (PCBs); 10.4. 2,3,7,8-TetrachIorodibenzo-p-dioxin (TCDD); 10.5. 2,3,7,8-Tetrachlorodibenzofuran (TCDF); 10.6. Polybrominated biphenyls (PBBs); 10.7. Mechanisms of immunotoxocity; 10.8. Conclusion; References; PART III: Human exposure and health effects; Chapter 11. General population exposure to environmental concentrations of halogenated biphenyls; 11.1 Introduction. |