Screen LibraryComputational biology of cancer：lecture notes and mathematical modeling
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| Main Authors: | |
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| Published: |
World Scientific,
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| Publisher Address: | Singapore Hackensack, NJ |
| Publication Dates: | c2005. |
| Literature type: | Book |
| Language: | English |
| Subjects: | |
| Carrier Form: | xiv, 250 p.: ill. ; 24 cm. |
| ISBN: | 9812560270 (alk. paper) |
| Index Number: | R730 |
| CLC: | R730 |
| Call Number: | R730/W838 |
| Contents: |
Includes bibliographical references (p. 227-245) and index. 1. Cancer and somatic evolution -- 2. Mathematical modeling of tumorigenesis -- 3. Cancer initiation: one-hit and two-hit stochastic models -- 4. Microsatellite and chromosomal instability in sporadic and familial cancers -- 5. Cellular origins of cancer -- 6. Costs and benefits of chromosomal instability -- 7. DNA damage and genetic instability -- 8. Tissue aging and the development of cancer -- 9. Basic models of tumor inhibition and promotion -- 10. Mechanisms of tumor neovascularization -- 11. Cancer and immune responses -- 12. Therapeutic approaches: viruses as anti-tumor weapons. |