Screen LibraryFlow chemistry for the synthesis of heterocycles /
This volume provides an overview of recent developments and scope in the use of flow chemistry in relevance to heterocyclic synthesis. The heterocyclic ring is the most prominent structural motif in the vast majority of natural products as well as pharmaceutical compounds since this facilitates tune...
Saved in:
| Group Author: | ; ; |
|---|---|
| Published: |
Springer,
|
| Publisher Address: | Cham, Switzerland : |
| Publication Dates: | [2018] |
| Literature type: | Book |
| Language: | English |
| Series: |
Topics in heterocyclic chemistry,
56 |
| Subjects: | |
| Summary: |
This volume provides an overview of recent developments and scope in the use of flow chemistry in relevance to heterocyclic synthesis. The heterocyclic ring is the most prominent structural motif in the vast majority of natural products as well as pharmaceutical compounds since this facilitates tuneable interactions with the biological target besides conferring a degree of structural and metabolic stability. In recent times, flow chemistry has heralded a paradigm shift in organic synthesis as it offers several unique advantages over conventional methods like drastic acceleration of sluggish |
| Carrier Form: | vii, 397 pages : illustrations (some color) ; 24 cm. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9783030068356 (paperback) : 3030068358 (paperback) 9783319943275 (hardcover) 3319943278 (hardcover) 9783319943282 (electronic book) 3319943286 (electronic book) |
| Index Number: | QD400 |
| CLC: | O626 |
| Call Number: | O626/F644 |
| Contents: | 1 Multistep Continuous-Flow Processes for the Preparation of Heterocyclic Active Pharmaceutical Ingredients -- 2 Photochemical Synthesis of Heterocycles: Merging Flow Processing and Metal-Catalyzed Visible Light Photoredox Transformations -- 3 Flow-Assisted Synthesis of Heterocycles via Multicomponent Reactions -- 4 Flow-Assisted Synthesis of Heterocycles at High Temperatures -- 5 Flow Chemistry Approaches Applied to the Synthesis of Saturated Heterocycles -- 6 Functionalization of Heteroarenes under Continuous Flow -- 7 Flow Chemistry as a Drug Discovery Tool: A Medicinal Chemistry Perspect |