Introduction to drug disposition and pharmacokinetics /

"The application of knowledge of drug disposition, and skills in pharmacokinetics, are crucial to the development of new drugs and to a better understanding of how to achieve maximum benefit from existing ones. The book takes the reader from basic concepts to a point where those who wish to wil...

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Bibliographic Details
Main Authors: Curry, Stephen H
Corporate Authors: Wiley InterScience Online service
Group Author: Whelpton, Robin
Published: Wiley,
Publisher Address: Chichester, West Sussex :
Publication Dates: [2017]
Literature type: eBook
Language: English
Subjects:
Online Access: http://onlinelibrary.wiley.com/book/10.1002/9781119261087
Summary: "The application of knowledge of drug disposition, and skills in pharmacokinetics, are crucial to the development of new drugs and to a better understanding of how to achieve maximum benefit from existing ones. The book takes the reader from basic concepts to a point where those who wish to will be able to perform pharmacokinetic calculations and be ready to read more advanced texts and research papers. The book will be of benefit to students of medicine, pharmacy, pharmacology, biomedical sciences and veterinary science, including those who have elected to study the topic in more detail, su
"The book takes the reader from basic concepts to a point where those who wish to will be able to perform pharmacokinetic calculations and be ready to read more advanced texts and research papers"--
Carrier Form: 1 online resource
Bibliography: Includes bibliographical references and index.
ISBN: 9781119261087
1119261082
9781119261056
1119261058
Index Number: RM301
CLC: R969.1
Contents: Drug Administration and Distribution -- Drug Metabolism and Excretion -- Single-compartment Pharmacokinetic Models -- Multiple-compartment and Non-compartment Pharmacokinetic Models -- Kinetics of Metabolism and Excretion -- Clearance, Protein Binding and Physiological Modelling -- Quantitative Pharmacological Relationships -- Pharmacokinetics of Large Molecules -- Pharmacogenetics and Pharmacogenomics -- Additional Factors Affecting Plasma Concentrations -- Effects of Age and Disease on Drug Disposition -- Drug Interactions and Toxicity -- Perspectives and Prospects -- Appendix 1: Mathemati