Combinatorial libraries : synthesis, screening and application potential /
Saved in:
Corporate Authors: | |
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Group Author: | |
Published: |
De Gruyter,
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Publisher Address: | Berlin/Boston : |
Publication Dates: |
[1996] ©1996 |
Literature type: | eBook |
Language: | English |
Subjects: | |
Online Access: |
http://dx.doi.org/10.1515/9783110808902 http://www.degruyter.com/doc/cover/9783110808902.jpg |
Carrier Form: |
1 online resource(xii,232pages) : illustrations Also available in print edition. |
Bibliography: | 92 schw.-w. Abb. |
ISBN: | 9783110808902 |
Index Number: | QP620 |
CLC: | Q52 |
Contents: |
Frontmatter -- Introduction -- Contents -- 1 Soluble Synthetic Combinatorial Libraries: The Use of Molecular Diversities for Drug Discovery / 2 Combinatorial Libraries of Synthetic Structures: Synthesis, Screening, and Structure Determination / 3 Peptide Libraries Bound to Continuous Cellulose Membranes: Tools to Study Molecular Recognition / 4 In Vitro Selection of Nucleic Acid Sequences that Bind Small Molecules / 5 Discovery and Characterization of a Thrombin Aptamer Selected from a Combinatorial ssDNA Library / 6 Structural and Functional Constraints in the Display of Peptides on Filamentous Phage Capsids / 7 Conformationally Defined Peptide Libraries on Phage: Selectable Templates for the Design of Pharmacological Agents / 8 Discovery of Disease-Specific Mimotopes by Screening Phage Libraries with Human Serum Samples / 9 The Utilization of Platelets and Whole Cells for the Selection of Peptides Ligands from Phage Display Libraries / 10 Identification of MHC Binding Motifs with Synthetic and Phage Displayed Peptide Libraries / 11 Isolating High Affinity Human Antibodies from Phage Repertoires / 12 Altering the Function of Enzymes and Macromolecular Inhibitors by Phage Display / Authors -- Index -- Backmatter. |