Screen LibraryComplement regulatory proteins /
From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of t...
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| Published: |
Academic Press,
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| Publisher Address: | San Diego : |
| Publication Dates: | 1999. |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://www.sciencedirect.com/science/book/9780125069656 |
| Summary: |
From small beginnings in the early 1970s, the study of complement regulatory proteins has grown in the last decade to the point where it dominates the complement field. This growth has been fueled by the discovery of new regulators, the cloning of old and new regulators, the discovery that many of the regulators are structurally and evolutionarily related to each other and the development of recombinant forms for use in therapy. There are now more proteins known to be involved in controlling the complement system than there are components of the system and the list continues to grow. The tim |
| Carrier Form: | 1 online resource (xiv, 382 pages) : illustrations |
| Bibliography: | Includes bibliographical references (pages 261-370) and index. |
| ISBN: |
9780125069656 0125069650 9781429498388 1429498382 0080529569 9780080529561 128103729X 9781281037299 |
| Index Number: | QR185 |
| CLC: | R392.1 |
| Contents: |
The Complement System: A Brief Overview: -- Introduction. -- Activation of C. -- Physiological Roles of C. -- Involvement of C in Pathology. -- Why a Book on C Regulators? -- Regulation in the Complement System: -- Introduction. -- History. -- Control of Activation Pathways. -- Control in the Membrane Attack Pathway. -- Control of the Anaphylactic Peptides. -- Summary. -- Regulation in the Activation Pathways: -- Regulation of C1. -- Regulators Encoded in the RCA Gene Cluster. -- Other Regulators of the Activation Pathways. -- Regulation in the Terminal Pathway: -- Introduction. -- Fluid-Pha Complement system: a brief overview -- Regulation in the complement system -- Regulation in the activation pathways -- Regulation in the terminal pathway -- Deficiencies of complement regulators -- Complement regulation in the reproductive system -- Complement regulators and micro-organisms -- Complement regulatory proteins in other species -- Complement regulators in therapy. |