Targeted therapies:mechanisms of resistance

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Bibliographic Details
Corporate Authors: SpringerLink (Online service)
Group Author: Gioeli Daniel.
Published: Humana Press,
Publisher Address: New York
Publication Dates: c2011.
Literature type: Book
Language: English
Series: Molecular and translational medicine
Subjects:
Online Access: http://dx.doi.org/10.1007/978-1-60761-478-4
Carrier Form: 1 online resource (xiv, 201 p.): ill. (some col.)
ISBN: 9781607614784 (electronic bk.)
1607614782 (electronic bk.)
Index Number: R96
CLC: R96
Contents: Includes bibliographical references and index.
Resistance to Targeted Therapies As a Result of Mutation(s) in the Target -- The Dynamics of the Cell Signaling Network; Implications for Targeted Therapies -- Cancer Signaling Network Analysis by Quantitative Mass Spectrometry -- Development and Implementation of Array Technologies for Proteomics: Clinical Implications and Applications -- Using Phosphoflow[tm] to Study Signaling Events of Subpopulations Resistant to Current Therapies -- Mathematical and Computational Models in Cancer -- Somatic Evolution of Acquired Drug Resistance in Cancer -- Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer -- microRNA: A Potential Therapy Able to Target Multiple Cancer Pathways -- Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance.