Targeted therapies:mechanisms of resistance
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Corporate Authors: | |
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Group Author: | |
Published: |
Humana Press,
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Publisher Address: | New York |
Publication Dates: | c2011. |
Literature type: | Book |
Language: | English |
Series: |
Molecular and translational medicine |
Subjects: | |
Online Access: |
http://dx.doi.org/10.1007/978-1-60761-478-4 |
Carrier Form: | 1 online resource (xiv, 201 p.): ill. (some col.) |
ISBN: |
9781607614784 (electronic bk.) 1607614782 (electronic bk.) |
Index Number: | R96 |
CLC: | R96 |
Contents: |
Includes bibliographical references and index. Resistance to Targeted Therapies As a Result of Mutation(s) in the Target -- The Dynamics of the Cell Signaling Network; Implications for Targeted Therapies -- Cancer Signaling Network Analysis by Quantitative Mass Spectrometry -- Development and Implementation of Array Technologies for Proteomics: Clinical Implications and Applications -- Using Phosphoflow[tm] to Study Signaling Events of Subpopulations Resistant to Current Therapies -- Mathematical and Computational Models in Cancer -- Somatic Evolution of Acquired Drug Resistance in Cancer -- Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer -- microRNA: A Potential Therapy Able to Target Multiple Cancer Pathways -- Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance. |