Screen LibraryAnimal models of movement disorders /
The use of animal models is a key aspect of scientific research in numerous fields of medicine. This book vigorously examines the important contributions and application of animal models to the understanding of human movement disorders and will serve as an essential resource for basic neuroscientist...
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| Corporate Authors: | |
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| Published: |
Elsevier Academic Press,
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| Publisher Address: | Burlington, MA : |
| Publication Dates: | 2005. |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://www.sciencedirect.com/science/book/9780120883820 |
| Summary: |
The use of animal models is a key aspect of scientific research in numerous fields of medicine. This book vigorously examines the important contributions and application of animal models to the understanding of human movement disorders and will serve as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. A vital feature o |
| Carrier Form: | 1 online resource (xiv, 806 pages) : illustrations |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: |
9780120883820 0120883821 9780080470566 0080470564 1280961198 9781280961199 |
| Index Number: | RC376 |
| CLC: | R742 |
| Contents: |
Preface; List of Contributors; A1: Classification and Clinical Features of Movement Disorders; A2: Animal Models and the Science of Movement Disorders; A3: Generation of Transgenic and Gene-Targeted Mouse Models of Movement Disorders; A4: Genetics of Spontaneous Mutations in Mice; A5: Assessment of Movement Disorders in Rodents; A6: Response Dynamics: Measurement of the Force and Rhythm of Motor Responses in Laboratory Animals; A7: Behavior in Drosophila : Analysis and Control; A8: Use of C. elegans to Model Human Movement Disorders; B1: The Phenotypic Spectrum of Parkinson Disease. B2: MPTP-Induced Nigrostriatal Injury in Nonhuman PrimatesB3: From Man to Mouse: The MPTP Model of Parkinson Disease; B4: Rotenone Rat and Other Neurotoxin Models of Parkinson Disease; B5: Drosophila Models of Parkinson Disease; B6: Phenotypical Characterization of Genetic Mouse Models of Parkinson Disease; B7: Utility of 6-Hydroxydopamine Lesioned Rats in the Preclinical Screening of Novel Treatments for Parkinson Dise. |