Screen LibraryHepatitis B virus : molecular mechanisms in disease and novelstrategies for therapy /
The book covers both the molecular aspects of hepatitis B virus replication and gene expression in vivo and in model systems, and the clinical impact of genetic variants or immunological response in chronic infection. Major emphasis is laid on the molecular mechanisms underlying hepatitis B virus-as...
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| Corporate Authors: | |
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| Group Author: | ; |
| Published: |
Imperial College Press ; Distributed by World Scientific Pub. Co.,
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| Publisher Address: | London : Singapore : |
| Publication Dates: | 1998. |
| Literature type: | eBook |
| Language: | English |
| Subjects: | |
| Online Access: |
http://www.worldscientific.com/worldscibooks/10.1142/P005#t=toc |
| Summary: |
The book covers both the molecular aspects of hepatitis B virus replication and gene expression in vivo and in model systems, and the clinical impact of genetic variants or immunological response in chronic infection. Major emphasis is laid on the molecular mechanisms underlying hepatitis B virus-associated liver carcinogenesis and their possible relevance to therapy and to the prevention of infection. Rational approaches to design novel vaccines or cytokine treatments, as well as strategies to develop vectors for liver-directed gene therapy, are discussed. |
| Carrier Form: | 1 online resource (viii,328pages) : illustrations |
| Bibliography: | Includes bibliographical references and indexes. |
| ISBN: | 9781848161078 |
| Index Number: | QR201 |
| CLC: | R512.6 |
| Contents: | I. Molecular biology of Hepatitis B virus. ch. 1. Replication of the Hepatitis B virus genome / Christoph Seeger and William S. Mason -- ch. 2. The regulation of Hepatitis B virus gene expression: an overview of the cis- and trans-acting components / Marshall J. Kosovsky, Ishtiaq Qadri and Aleem Siddiqui -- ch. 3. Animal models and experimental systems in Hepatitis B virus research / Stephan Schaefer, Tanja Tolle, Stefan Lottmann and Wolfram H. Gerlich -- II. Infection and chronic disease. ch. 4. Natural course of HBV infection / Hubert E. Blum, Stefan Wieland, Eike Walter, Fritz von Weizsac |