Genomics, proteomics, and vaccines

While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come.℗¡Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have t...

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Bibliographic Details
Group Author: Grandi, Guido.
Published:
Literature type: Electronic eBook
Language: English
Subjects:
Online Access: http://onlinelibrary.wiley.com/book/10.1002/0470012536
Summary: While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come.℗¡Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly.
Carrier Form: 1 online resource (xxi, 313 pages) : illustrations
Bibliography: Includes bibliographical references and index.
ISBN: 0470093927
9780470093924
0470856165
9780470856161
0470012536
9780470012536
Index Number: QH447
CLC: Q78
Contents: Section I. Introduction -- 1. Vaccination : past, present and future / Maria Lattanzi and Rino Rappuoli -- 2. Bioinformatics, DNA microarrays and proteomics in vaccine discovery : competing or complementary technologies? / Guido Grandi -- Section II. Technologies -- 3. Genome sequencing and analysis / Herve Tettelin and Tamara Feldblyum -- 4. Understanding DNA Microarrays : Sources and Magnitudes of Variances in DNA Microarray Data Sets / She-pin Hung [and others] -- 5. The proteome, anno domini two zero zero three / Pier Giorgio Righetti [and others] -- 6. Mass spectrometry in proteomics / Pierre-Alain Binz -- 7. High Throughput Cloning, Expression and Purification Technologies / Andreas Kreusch and Scott A. Lesley -- Section III. Applications -- 8. Meningococcus B : from Genome to Vaccine / Davide Serruto, Rino Rappuoli and Mariagrazia Pizza -- 9. Vaccines Against Pathogenic Streptococci / John L. Telford [and others] -- 10. Proteome analysis of outer membrane and extracellular proteins from Pseudomonas aeruginosa for vaccine discovery / Stuart J. Cordwell and Amanda S. Nouwens -- 11. Proteomics and anti-Chlamydia vaccine discovery / Gunna Christiansen [and others] -- 12. Searching the Chlamydia genomes for new vaccine candidates / Giulio Ratti, Oretta Finco and Guido Grandi -- 13. Identification of the "antigenome" : a novel tool for design and development of subunit vaccines against bacterial pathogens / Eszter Nagy [and others].